Expression of Nitric Oxide Synthases in Nasal Polyp
نویسندگان
چکیده
منابع مشابه
Perspective Series: Nitric Oxide and Nitric Oxide Synthases Nitric Oxide Synthases: Which, Where, How, and Why?
Although nitric oxide (NO) 1 may not modulate all cellular functions and may not be present in all mammalian cells, the sheer volume of publications on the subject might lead one to conclude that this diminutive molecule is both omnipotent and omnipresent in human biology. This series of four Perspective articles, in the current and following issues of The Journal of Clinical Investigation , wi...
متن کاملNitric oxide synthases in mammals.
Nitric oxide is an inorganic free radical gas, of formula *N=O (abbreviated as NO). The discovery in 1987/88 that vascular endothelial cells are able to synthesize NO from L-arginine as a transcellular signal [1-4] was initially received by most biologists with considerable scepticism. By now, however, the existence of the L-arginine:NO pathway has been thoroughly documented and its relevance i...
متن کاملNitric oxide in fracture repair. Differential localisation, expression and activity of nitric oxide synthases.
Our aim was to investigate whether nitric oxide synthase (NOS) isoforms, responsible for the generation of NO, are expressed during the healing of fractures. To localise the sites of expression compared with those in normal bone we made standardised, stabilised, unilateral tibial fractures in male Wistar rats. Immunostaining was used to determine the precise tissue localisation of the different...
متن کاملSignificance of nitric oxide synthases: Lessons from triple nitric oxide synthases null mice.
Nitric oxide (NO) is synthesized by three distinct NO synthases (neuronal, inducible, and endothelial NOSs), all of which are expressed in almost all tissues and organs in humans. The regulatory roles of NOSs in vivo have been investigated in pharmacological studies with non-selective NOS inhibitors. However, the specificity of the inhibitors continues to be an issue of debate, and the authenti...
متن کاملPerspective Series: Nitric Oxide and Nitric Oxide Synthases
Although nitric oxide (NO) 1 may not modulate all cellular functions and may not be present in all mammalian cells, the sheer volume of publications on the subject might lead one to conclude that this diminutive molecule is both omnipotent and omnipresent in human biology. This series of four Perspective articles, in the current and following issues of The Journal of Clinical Investigation , wi...
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ژورنال
عنوان ژورنال: Journal of Clinical Otolaryngology Head and Neck Surgery
سال: 2002
ISSN: 1225-0244,2713-833X
DOI: 10.35420/jcohns.2002.13.1.85